Thursday, November 1, 2007

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Initial studies on the human genome sequencing led to the conclusion that there appeared to be a wide variation in the genome sequence between individuals and therefore, regardless of our race, humans were genetically equal to 99.9%. However, if our genome, our DNA is so similar why we seem so different in some respects? The answer seems to be slowly reeled through detailed studies of the sequence of many individuals of different races and different parts the globe, analyzed based on a catalog of small changes that have been detected in the DNA. These variations are called polymorphisms , most affect only one DNA base, a code letter, are known by the acronym SNP . In many cases, these modifications of the same gene are clearly detectable, so there are variations in eye color or blood type. In other cases, the changes constitute a disease, as the case of hemophilia or express a greater likelihood of developing a disease. However, the largest proportion of changes are hidden in our DNA, and which are not reflected in a characteristic distinctive human. Recent research published this month in the journal Nature (vol 449: pg. 851), analyzing the genomes of 270 people from around the world indicate that the variation in these polymorphisms, SNPs, may be higher than expected . Do not talk about specific numbers and hopes to expand this study. It would be interesting conclusions that allow us to learn more about our evolution and how to combat certain diseases associated with the structure and sequence the human genome. Use these studies to support or eugenic racist is nonsense that we should protect ourselves. Dr James Watson , awarded the Nobel for his discoveries about the DNA structure in 1962 with just 34, recently had a "slip" in this sense, improperly mixing races and genomes, their statements have had great media coverage, given his position and have led to an interesting debate translates into in general is gaining significance day by day in our society the knowledge gained from sequencing the human genome. The company must use in the future all means that these studies represent a real advancement of knowledge and they will never to the detriment of our freedom or our privacy.

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