Recently, reprogramming of adult differentiated cells, such as our skin cells to turn them into pluripotent cells, like embryonic cells that can differentiate into any cell type has Of course great hope because it could use these cells, called iPS (induced Pluripotent Stem cells ) or induced pluripotent cells in cell therapy for many diseases. imagine that could take a skin cells from a patient with cirrhosis and transform them into hepatocytes or that otherwise could convert these cells into cardiomyocytes in the case of a patient who has suffered a myocardial infarction. Functional reprogrammed cells could, once implanted, to recover the affected organ without immune rejection and no ethical problems that arise with the use of embryonic stem cells important humanas.Dos initial problems arose with iPS cells, the first was that to make cell reprogramming needed retrovirus to introduce specific genes for reprogramming, as well as between these genes were some, called a c-myc, which is associated with tumor formation. Recently there have been significant in the formation of such iPS cells, first trying to avoid the use of viruses and partly by eliminating genes that may relate to tumores.Es Interestingly, many of the results on the generation of this type iPS cells suggest that the mechanisms causing reprogramming are consistent with the processes by which tumor cells arise. For example, it was recently revealed that one of the genes whose dysfunction is associated with cancer , called p53, also promotes the reprogramming iPS cells where their activity in these cells is decreased. The reprogramming process is jump iPS cells have mechanisms to avoid division into uncontrolled situations, hence the overlap with cancer. It may be precisely that we are rating the potential use of iPS cells in cell therapy, studies on the reprogramming of these cells allows us to unravel the pathological mechanisms by which some cells in our body are skipped safety checks and cause cancer This would combat the disease naturally.
